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This is the same lobe of Calmodulin in the Ca2+ state. Note how the colouring has changed completely and there is a large white hydrophobic patch for target binding and large binding pocket has been formed. You can now see how as well as changing the overall structure of the protein the addition of Calcium changes the binding surface dramatically.

RED=Negative BLUE=Positive YELLOW=Polar WHITE=Hydrophobic

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